Mesothelioma Clinical Trials

Status Title Age Phase
Active, not recruiting Active Symptom Control With or Without Chemotherapy in Treating Patients With Malignant Pleural Mesothelioma Adult/Senior Phase III
Active, not recruiting Alanosine in Treating Patients With Cancer Child/Adult/Senior Phase II
Active, not recruiting AZD2171 in Treating Patients With Malignant Pleural Mesothelioma That Cannot Be Removed By Surgery Adult/Senior Phase II
Active, not recruiting Bevacizumab (Avastin) and Erlotinib (Tarceva) in Previously Treated Mesothelioma Adult/Senior Phase II
Active, not recruiting Biomarkers of Angiogenesis and Disease in Patients With Unresectable Malignant Mesothelioma Treated on Clinical Trial CALGB-30107 Adult/Senior
Active, not recruiting Capecitabine in Treating Patients With Malignant Mesothelioma Adult/Senior Phase II
Active, not recruiting Cisplatin With or Without Raltitrexed in Treating Patients With Malignant Mesothelioma of the Pleura Adult/Senior Phase III
Active, not recruiting Cisplatin, Interferon Alfa, Surgery, and Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma Adult/Senior Phase I
Active, not recruiting Combination Chemotherapy Before Surgery in Treating Patients With Mesothelioma of the Lung Adult/Senior Phase II
Active, not recruiting Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Malignant Mesothelioma Adult/Senior Phase II
Active, not recruiting Combination Chemotherapy With or Without Surgery and Chemoradiotherapy in Treating Patients With Malignant Pleural Mesothelioma Child/Adult/Senior Phase II
Active, not recruiting Combination Chemotherapy With or Without Surgery and Radiation Therapy in Treating Patients With Mesothelioma That Can Be Removed By Surgery Adult/Senior
Active, not recruiting Extrapleural Pneumonectomy With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Amifostine and Sodium Thiosulfate Adult/Senior Phase II
Active, not recruiting Gemcitabine Plus Cisplatin in Treating Patients With Malignant Mesothelioma of the Pleura That Cannot Be Removed by Surgery Adult/Senior Phase II
Active, not recruiting High-Dose Megestrol in Treating Patients With Metastatic Breast Cancer, Endometrial Cancer, or Mesothelioma Adult/Senior Phase I/Phase II
Active, not recruiting Interleukin-12 in Treating Patients With Cancer in the Abdomen Adult/Senior Phase I
Active, not recruiting Intrapleural BG00001 in Treating Patients With Malignant Pleural Mesothelioma or Malignant Pleural Effusions Adult/Senior Phase I
Active, not recruiting Liposomal-Cisplatin Analogue (L-NDDP) in Treating Patients With Malignant Pleural Mesothelioma Adult/Senior Phase II
Active, not recruiting Molecular Predictors of Pemetrexed and Carboplatin Response in Tumor Samples of a Series of Malignant Pleural Mesothelioma (MPM) Patients and Genotyping for the TSER Polymorphism Adult/Senior
Active, not recruiting Neoadjuvant Pemetrexed Disodium and Cisplatin Followed by Surgery and Radiation Therapy in Treating Patients With Pleural Mesothelioma Adult/Senior Phase II
Active, not recruiting ONCONASE Plus Doxorubicin Versus Doxorubicin Alone For Patients With Malignant Pleural or Peritoneal Mesothelioma Who Have Had No More Than One Prior Chemotherapy Regimen Adult/Senior Phase III
Active, not recruiting Palliative Therapy With or Without Chemotherapy in Treating Patients With Malignant Mesothelioma Child/Adult/Senior Phase II
Active, not recruiting Palliative Treatment With Liposomal Doxorubicin Plus Cisplatin for Patients With Malignant Pleural Mesothelioma Adult/Senior Phase II
Active, not recruiting Pazopanib in Treating Patients With Malignant Pleural Mesothelioma Adult/Senior Phase II
Active, not recruiting Pemetrexed Disodium and Cisplatin Followed By Surgery and Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma Child/Adult/Senior Phase II
Active, not recruiting Pemetrexed Disodium and Either Gemcitabine or Carboplatin in Treating Patients With Advanced Malignant Pleural Mesothelioma Adult/Senior Phase II
Active, not recruiting Pemetrexed Disodium and Gemcitabine in Treating Patients With Malignant Mesothelioma Adult/Senior Phase II
Active, not recruiting Pemetrexed Plus Cisplatin Neoadjuvant Therapy Followed By Surgery and Radiation in Mesothelioma Adult/Senior Phase II
Active, not recruiting Phase I Study of OSI-930 and Erlotinib in Cancer Tumors Adult/Senior Phase I
Active, not recruiting Phase II Study of Valproate and Doxorubicin in Malignant Mesothelioma Adult/Senior Phase II
Active, not recruiting Pleurectomy/Decortication Followed by Intrathoracic/Intraperitoneal Heated Cisplatin for Malignant Pleural Mesothelioma Adult/Senior Phase I
Active, not recruiting Printed Education Materials in Patients Who Are Finishing Treatment for Stage I, Stage II, or Stage IIIA Breast Cancer, Colorectal Cancer, Prostate Cancer, or Chest Cancer Adult/Senior
Active, not recruiting PTK787/ZK 222584 in Treating Patients With Unresectable Malignant Mesothelioma Adult/Senior Phase II
Active, not recruiting Radiation Therapy in Preventing Metastatic Cancer in Patients Who Have Diagnostic Procedures to Identify Malignant Mesothelioma Child/Adult/Senior Phase III
Active, not recruiting Radiofrequency Ablation in Treating Patients With Refractory or Advanced Lung Cancer Child/Adult/Senior Phase II
Active, not recruiting Raltitrexed in Treating Patients With Malignant Mesothelioma That Cannot Be Surgically Removed Adult/Senior Phase II
Active, not recruiting Rapamycin With Grapefruit Juice for Advanced Malignancies Adult/Senior Phase I
Active, not recruiting Response Evaluation in Malignant Pleural Mesothelioma Adult/Senior
Active, not recruiting Safety and Immune Response to a Multi-component Immune Based Therapy (MKC1106-PP) for Patients With Advanced Cancer. Adult/Senior Phase I
Active, not recruiting Sorafenib in Previously Treated Malignant Mesothelioma Adult/Senior Phase II
Active, not recruiting Sorafenib in Treating Patients With Malignant Mesothelioma Adult/Senior Phase II
Active, not recruiting Study of NGR-hTNF as Single Agent in Patients Affected by Advanced or Metastatic Malignant Pleural Mesothelioma Adult/Senior Phase II
Active, not recruiting Surgery and Photodynamic Therapy in Treating Patients With Malignant Mesothelioma Adult/Senior Phase II
Active, not recruiting Surgery, Chemotherapy, and Radiation Therapy in Treating Patients With Peritoneal Cancer Adult/Senior Phase II
Active, not recruiting Vaccine Therapy and Ganciclovir in Treating Patients With Mesothelioma Child/Adult/Senior Phase I
Active, not recruiting Vaccine Therapy in Treating Patients With Stage I, Stage II, or Stage IIIA Non-Small Cell Lung Cancer or With Stage I or Stage II Mesothelioma Adult/Senior Phase I
Active, not recruiting Weekly Oxaliplatin and Gemcitabine for Recurrent or Metastatic Head and Neck Cancer Adult/Senior Phase II
Approved for marketing ALIMTA (Pemetrexed) Alone or in Combination With Cisplatin for Patients With Malignant Mesothelioma. Adult/Senior Phase II
Completed A Study Comparing Pemetrexed Plus Best Supportive Care Versus Best Supportive Care Alone in the Treatment of Mesothelioma Adult/Senior Phase III
Completed A Study of MORAb-009 in Subjects With Pancreatic Cancer, Mesothelioma, or Certain Types of Ovarian or Lung Cancer Adult/Senior Phase I
Completed An Open-Label, Phase II Trial of ZD1839 (IRESSA) in Patients With Malignant Mesothelioma Adult/Senior Phase II
Completed Cisplatin With or Without Pemetrexed Disodium in Treating Patients With Malignant Mesothelioma of the Pleura That Cannot be Removed by Surgery Adult/Senior Phase III
Completed Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors Child/Adult Phase II
Completed Cyclophosphamide Plus Vaccine Therapy in Treating Patients With Advanced Cancer Adult/Senior Phase II
Completed Decitabine in Treating Patients With Unresectable Lung or Esophageal Cancer or Malignant Mesothelioma of the Pleura Adult/Senior Phase I
Completed Ecteinascidin 743 in Treating Patients With Malignant Mesothelioma Adult/Senior Phase II
Completed EF5 in Detecting Oxygen Level and Blood Vessels in Tumor Cells of Patients Undergoing Photodynamic Therapy for Intraperitoneal or Pleural Cancer Adult/Senior
Completed Erlotinib in Treating Patients With Malignant Mesothelioma of the Lung Child/Adult/Senior Phase II
Completed Gefitinib in Treating Patients With Malignant Mesothelioma Adult/Senior Phase II
Completed Gemcitabine and Epirubicin in Treating Patients With Malignant Mesothelioma Adult/Senior Phase II
Completed Immunotoxin Therapy in Treating Patients With Advanced Cancer Adult/Senior Phase I
Completed Immunotoxin Therapy in Treating Patients With Advanced Solid Tumors Adult/Senior Phase I
Completed Inhaled Doxorubicin in Treating Patients With Advanced Solid Tumors Affecting the Lungs Adult/Senior Phase I
Completed MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma Adult/Senior Phase I
Completed Pemetrexed Plus Gemcitabine as Front-Line Chemotherapy for Patients With Malignant Pleural or Peritoneal Mesothelioma Adult/Senior Phase II
Completed Pharmacokinetic, Safety, and Efficacy Effects of Oral LBH589 on Dextromethorphan in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer or Malignant Pleural Mesothelioma Adult/Senior Phase I
Completed Phase II Study of Imatinib Mesylate in Patients With Life Threatening Malignant Rare Diseases Child/Adult/Senior Phase II
Completed Phase II Trial of Neo-Adjuvant Pemetrexed Plus Cisplatin Followed by Surgery and Radiation for Pleural Mesothelioma Adult/Senior Phase II
Completed PV701 in Treating Patients With Advanced or Recurrent Peritoneal Cancer Adult/Senior Phase I
Completed PXD101 as Second-Line Therapy in Treating Patients With Malignant Mesothelioma of the Chest That Cannot Be Removed By Surgery Adult/Senior Phase II
Completed Rigid Thoracoscopy Versus CT-Guided Pleural Needle Biopsy Adult/Senior
Completed Safety Confirmation Study of Pemetrexed Plus Cisplatin in Patients With Malignant Pleural Mesothelioma Adult/Senior Phase II
Completed Study of Pemetrexed in Mesothelioma and Lung Cancer Patients With Fluid Around the Lungs or Abdomen Adult/Senior Phase II
Completed Study of Pemetrexed Plus Cisplatin in Patients With Malignant Pleural Mesothelioma Adult/Senior Phase I/Phase II
Completed Study of PXD101 Alone and in Combination With 5-Fluorouracil (5-FU) in Patients With Advanced Solid Tumors Adult/Senior Phase I
Completed SU5416 in Treating Patients With Malignant Mesothelioma Adult/Senior Phase II
Completed Suberoylanilide Hydroxamic Acid in Advanced Solid Tumors Adult, Senior Phase I
Completed Vaccine Therapy and GM-CSF in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndromes, Non-Small Cell Lung Cancer, or Mesothelioma Adult/Senior Phase I
Enrolling by invitation Study of Previously Collected and Stored Tissue Samples From Patients Previously Enrolled in a Completed National Cancer Institute Clinical Trial Adult/Senior
Not yet recruiting A Phase II Study of the Association of Glivec® Plus Gemzar® in Patients With Unresectable, Refractory, Malignant Mesothelioma Adult/Senior Phase II
Not yet recruiting A Study of Cetuximab Combined With Cisplatin or Carboplatin/Pemetrexed as First Line Treatment in Patients With Malignant Pleural Mesothelioma. Adult/Senior Phase II
Not yet recruiting N-AcetylCysteine vs. Placebo to Prevent Neurotoxicity Induced by Platinum Containing Chemotherapy Adult/Senior
Not yet recruiting Pemetrexed Disodium and Cisplatin With or Without Cediranib Maleate in Treating Patients With Malignant Pleural Mesothelioma Adult/Senior Phase I/Phase II
Not yet recruiting Pemetrexed Disodium or Observation in Treating Patients With Malignant Pleural Mesothelioma Without Progressive Disease After First-Line Chemotherapy Adult/Senior Phase II
Not yet recruiting Sunitinib and Hydroxychloroquine in Treating Patients With Advanced Solid Tumors That Have Not Responded to Chemotherapy Adult/Senior Phase I
Recruiting 1-Methyl-d-Tryptophan in Treating Patients With Relapsed or Refractory Solid Tumors Adult/Senior Phase I
Recruiting A Study To Find The Best Dose Of SU011248 When Given With Pemetrexed, Pemetrexed And Cisplatin Or Pemetrexed And Carboplatin In Patients With Advanced Solid Tumors Adult/Senior Phase I
Recruiting An Analysis of the Response of Human Tumor Microvascular Endothelium to Ionizing Radiation Adult/Senior Phase III
Recruiting An Efficacy and Safety Study With Vandetanib to Treat Inoperable or Relapsed Malignant Mesothelioma Adult/Senior Phase II
Recruiting An Efficacy Study of Milataxel (TL139) Administered Orally for Malignant Mesothelioma Adult/Senior Phase II
Recruiting An Efficacy Study of MORAb-009 in Subjects With Pleural Mesothelioma Adult/Senior Phase II
Recruiting An Open-Label Clinical Trial of MORAb-009 in Combination With Pemetrexed and Cisplatin in Subjects With Mesothelioma Adult/Senior Phase II
Recruiting Antineoplaston Therapy in Treating Patients With Advanced Mesothelioma Child/Adult/Senior Phase II
Recruiting AZD2171 in Treating Patients With Malignant Mesothelioma That Cannot Be Removed By Surgery Adult/Senior Phase II
Recruiting Biomarkers to Detect Mesothelioma Early in Patients Exposed to Asbestos or Vermiculite Adult/Senior
Recruiting Bortezomib and Cisplatin as First-Line Therapy in Treating Patients With Malignant Mesothelioma Adult/Senior Phase II
Recruiting Bortezomib in Treating Patients With Malignant Pleural Mesothelioma Adult/Senior Phase II
Recruiting Carboplatin, Bevacizumab and Pemetrexed in the First-Line Treatment of Patients With MPM Adult/Senior Phase I/Phase II
Recruiting Cisplatin, Pemetrexed and Bevacizumab for Untreated Malignant Mesothelioma Adult/Senior Phase II
Recruiting Cisplatin, Pemetrexed, and Imatinib Mesylate in Malignant Mesothelioma Adult/Senior Phase I
Recruiting Collecting Tumor Samples From Patients With Gynecological Tumors Child/Adult/Senior
Recruiting Continuous Hyperthermic Peritoneal Perfusion (CHPP) With Cisplatin for Children With Peritoneal Cancer Child/Adult Phase I
Recruiting Dasatinib in Resectable Malignant Pleural Mesothelioma Adult/Senior Phase I
Recruiting Dasatinib in Treating Patients With Previously Treated Malignant Mesothelioma Adult/Senior Phase II
Recruiting Decitabine and FR901228 in Treating Patients With Advanced Lung Cancer, Esophageal Cancer, Pleural Mesothelioma, or Lung Metastases Adult/Senior Phase I
Recruiting Dendritic Cell-Based Immunotherapy in Mesothelioma Adult/Senior Phase I
Recruiting Early Diagnosis of Lung Cancer and Mesothelioma in Prior Asbestos Workers Adult/Senior
Recruiting Electronic Tool to Record Cancer Symptoms in Patients With Advanced Cancer Receiving Palliative Care Adult/Senior Phase III
Recruiting Eloxatin® Plus Gemcitabine Chemotherapy for Mesothelioma Adult/Senior Phase II
Recruiting Everolimus (RAD001) for the Treatment of Malignant Pleural Mesothelioma With Merlin/NF2 Loss as a Biomarker to Predict Sensitivity Adult/Senior Phase II
Recruiting Everolimus in Treating Patients With Pleural Malignant Mesothelioma That Cannot Be Removed By Surgery Adult/Senior Phase II
Recruiting Extrapleural Pneumonectomy /Pleurectomy Decortication, IHOC Cisplatin and Gemcitabine With Amifostine and Sodium Thiosulfate Cytoprotection for Resectable Malignant Pleural Mesothelioma Adult/Senior Phase I
Recruiting Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Adult/Senior Phase III
Recruiting FR901228 and Flavopiridol in Treating Patients With Advanced Lung, Esophageal, or Pleural Cancer Adult/Senior Phase I
Recruiting Gene Therapy for Pleural Malignancies Adult/Senior Phase I
Recruiting Immunotoxin Therapy, Pemetrexed, and Cisplatin in Treating Patients With Malignant Pleural Mesothelioma That Cannot Be Removed by Surgery Adult/Senior Phase I
Recruiting Mesothelin and Osteopontin as Diagnostic Markers in Patients With Mesothelioma or Atypical Mesothelial Hyperplasia Child/Adult/Senior
Recruiting Mesothelioma Avastin Plus Pemetrexed-Cisplatin Study Adult/Senior Phase II/Phase III
Recruiting Optical Coherence Tomography of the Airway in Detecting Abnormal Cells in Patients Undergoing Surgery for Lung Cancer or Lung Disease Child/Adult/Senior Phase I
Recruiting Pemetrexed (ALIMTA) Plus Cisplatin Followed by Surgery and Radiation Therapy for Mesothelioma Adult/Senior Phase II
Recruiting Pemetrexed Disodium and Cisplatin Followed by Surgery With or Without Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma Adult/Senior Phase II
Recruiting Pemetrexed, Cisplatin, and Vitamin B12 in Treating Patients With Mesothelioma of the Chest That Cannot Be Removed by Surgery Adult/Senior Phase II
Recruiting Phase I Dose-Escalation Study Of Azacitidine In Combination With Temozolomide Adult/Senior Phase I
Recruiting Phase II Study of Bevacizumab, Pemetrexed and Carboplatin as First-Line Therapy in Malignant Pleural Mesothelioma Adult/Senior Phase II
Recruiting Pleurectomy/Decortication With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Sodium Thiosulfate Adult/Senior Phase II
Recruiting Short Neoadjuvant Hemithoracic IMRT for MPM Adult/Senior Phase I/Phase II
Recruiting Sorafenib, Pemetrexed, and Cisplatin in Treating Patients With Advanced Solid Tumors Adult/Senior Phase I
Recruiting Study of Carboplatin and Vinorelbine in Malignant Pleural Mesothelioma Adult/Senior Phase II
Recruiting Study of CBP501 + Pemetrexed + Cisplatin in Patients With Solid Tumors (Phase I) and Patients With Malignant Pleural Mesothelioma (Phase II) Adult/Senior Phase I/Phase II
Recruiting Study of Oral PXD101 in Patients With Advanced Solid Tumors or Lymphoma Adult/Senior Phase I
Recruiting Study of Patients With Non-Small Cell Lung Cancer, Esophageal Cancer, Malignant Pleural Mesothelioma, Mediastinal or Chest Wall Neoplasms, or Lung Metastases From Cancers of Non-Thoracic Origin Child/Adult/Senior
Recruiting Study of Pemetrexed and Bevacizumab in Patients With Head and Neck Cancer Adult/Senior Phase II
Recruiting Study of Pemetrexed for Second-Line Pancreas Cancer Adult/Senior Phase II
Recruiting Study Using Chemotherapy Followed by Intensity Modulated Radiation Therapy to the Pleura in Patients With Locally Advanced But Unresectable Malignant Pleural Mesothelioma Adult/Senior Phase II
Recruiting Suberoylanilide Hydroxamic Acid (SAHA) Versus Placebo in Advanced Malignant Pleural Mesothelioma Adult/Senior Phase III
Recruiting Surgery Plus Intraoperative Peritoneal Hyperthermic Chemotherapy (IPHC) to Treat Peritoneal Carcinomatosis Adult/Senior Phase II
Recruiting Tomotherapy Treatment for Mesothelioma Adult/Senior Phase II
Recruiting Trimodal Lung-Sparing Treatment of Pleural Mesothelioma Adult/Senior Phase II
Recruiting Triplet Combination First Line Treatment in Non Small Cell Lung Cancer (NSCLC) Adult/Senior Phase II
Recruiting Velcade and Eloxatin for Patients With Malignant Pleural or Peritoneal Mesothelioma Adult/Senior Phase II
Recruiting Video-Assisted Surgery or Talc Pleurodesis in Treating Patients With Malignant Mesothelioma Adult/Senior Phase III
Suspended Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney Dysfunction Adult/Senior Phase I
Suspended Flavopiridol in Treating Patients With Metastatic or Unresectable Refractory Solid Tumors or Hematologic Malignancies Adult/Senior Phase I
Suspended Phase I/II Trial of PTK787 and Pemetrexed With or Without Cisplatin for Lung Cancer Adult/Senior Phase I/Phase II
Suspended Sunitinib in Treating Patients With Advanced Malignant Pleural Mesothelioma Adult/Senior Phase II
Terminated CryoSpray Ablation(tm)in Malignant Airway Disease to Determine Safety, and Tissue Effect in the Lung (ICE the MAD) Adult/Senior Phase IV
Terminated Study of Safety and Tolerability of Intravenous CRS-207 in Adults With Selected Advanced Solid Tumors Who Have Failed or Who Are Not Candidates for Standard Treatment Adult/Senior Phase I
Terminated Study of SS1(dsFv)-PE38 (SS1P) Anti-Mesothelin Immunotoxin in Advanced Malignancies: Continuous Infusion for 10 Days Adult/Senior Phase I
Terminated Study of SS1(dsFv)-PE38 (SS1P) Anti-Mesothelin Immunotoxin in Advanced Malignancies: IV Infusion QOD x Six Doses Adult/Senior Phase I
Withdrawn A Study of VEGF-Antisense Oligonucleotide in Combination With Pemetrexed and Cisplatin for the Treatment of Advanced Malignant Mesothelioma Adult/Senior Phase I/Phase II
Withdrawn CryoSpray Ablation(tm)Thoracic Patient Registry Adult/Senior

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